Neil Theise, MD is senior author of the article “Structure and Distribution of an Unrecognized Interstitium in Human Tissues” recently published in the journal Scientific Reports. He is a diagnostic liver pathologist and adult stem cell researcher in New York City, where he is Professor of Pathology at New York University School of Medicine. His research revised understandings of human liver microanatomy which, in turn, led directly to identification of possible liver stem cell niches and the marrow-to-liver regeneration pathway. He is considered a pioneer of multi-organ adult stem cell plasticity and has published on that topic in Science, Nature, and Cell.
Subsequently, while continuing laboratory and clinical research, he has extended his work to areas of theoretical biology and complexity theory, defining a “post-modern biology.” These ideas suggest that alternate models of the body, other than Cell Doctrine, may be necessary to understand non-Western approaches to the body and health. Current laboratory investigations focus on nerve-stem cell interactions in human livers, melatonin-related physiology of human liver stem cell and regenerative processes, and aspects of human liver stem cell activation in acute, fulminant hepatic failure.